Courses Detailed Description

 

 
 

PHENOMENOLOGICAL PHILOSOPHY AND THE CONTEMPORARY PROBLEM OF THE INTENTIONALITY OF THE MINDTop of the page

Course Master:
F. Vassileiou
Duration:
1 semester
ECTS (credit hours):
6 (30)
Course outline:
1. Basic elements of Philosophy of Science
The problem of induction and the first principles: Application in the case of Cognitive Science.
 
2. Descriptive Psychology and Franz Brentano’s peculiar empiricism
Inner perception, stratification of mental life, presentation, judgment.
 
3. Brentano’s legacy
Psychical phenomena, physical phenomena, and intentionality as criterion for the delineation of the region of psychical acts.
 
4. Edmund Husserl’s criticism against Brentano’s theory (Ι)
First form of psychologism and its overcoming: eidetic method and Husserl’s critique of naturalism.
 
5. Edmund Husserl’s criticism against Brentano’s theory (ΙΙ)
Second form of psychologism and its overcoming: synthetic categorial intuition. Simple perception, judgment, scientific idealization.
 
6. The issue of perceptual intentionality
Gestalt Psychology and Husserlian Mereology.
 
7. Different levels of the phenomenological constitution of perceptual objects
Sensory fields, primordial extentionality, and primordial materiality-causality.
 
8. Reception of the problem of intentionality in the analytic tradition
The way Roderick Chisholm construed Brentano’s theory. The formation of contemporary representational theory of mind.
 
9. The current discussion about the distinction between conceptual and non-conceptual perceptual content in analytic philosophy
The “myth of the given,” John McDowell’s intellectualism, and recent tendencies of acceptance of non-conceptual content.
 
10. The attempt at a dialogue between phenomenology and analytic philosophy regarding the distinction between conceptual and non-conceptual content
Tendencies for convergence and criticism.
 
 

11. Overall reconstructive discussion

Instructors:
F.Vassiliou
Prerequisites:

 

NEUROPSYCHOLOGICAL EVALUATIONTop of the page

Course Master:
Panagiotis Simos, Ph.D
Duration:
1 semester
 
ECTS (credit hours):

9 (45)
Course outline:
The course covers the basic principles of psychometric theory involved in the application of standardized tests for the assessment of language and cognitive functions. Specific applications of these tests in the evaluation of patients with neurological disorders are discussed.
Instructors:
Panagiotis Simos, Ph.D.
Prerequisites:
Clinical Neuroanatomy, Brain and cognitive functions

 

Μusculoskeletal biomechanics - NEUROMECHANICS OF MOVEMENTTop of the page

Course Master:
G.M. Kontakis
Duration:
1 semester
ECTS (credit hours):
6 (30)
Course outline:
1. Biomechanics of human movement and analysis of muscle and joint loads

Describing motion

Movement forces

Forces within the body

2. Biomechanics of the musculoskeletal tissues

Bone, articular cartilage

Ligaments and tendons

Muscles, neural tissue

3. Biomaterials and biomechanics of the artificial joints (endoprostheses)
4. Adabtability of the motor system in response of physical activity
5. Kinesiology of the upper extremity
6. Kinesiology of the spine and the lower extremity
7. Posture and gait
Instructors:
G.M. Kontakis
References
V. C. Mow and R. Huiskes: Basic Orthopaedic Biomechanics and Mechano-Biology, 3rd Edition, LWW 2005. C.A. Oatis: Kinesiology- the mechanics and pathomechanics of the human movement, 2nd Edition, LWW 2009. D. Elliott and M. Khan (Editors): Vision and Goal-Directed Movement, Human Kinetics 2010. R. Evoka:Neuromechanics of human movement, 4th Edition,Human Kinetics 2008

 

HUMAN PHYSIOLOGY OF MOVEMENT AND PATHOPHYSIOLOGY OF MOVEMENT DISORDERSTop of the page

Course Master:
D. Anastasopoulos
Duration:
1 semester
 
ECTS (credit hours):

6 (30)
Course outline:
Mechanical properties of muscles and their effects on control of movements
Motor unit. Its pathophysiology. Electromyographic investigations in peripheral nerve and muscle diseases.
Sensory control of motor units
Pathophysiology of spinal reflexes
Balance and postural reflexes
Cortical control of movement
Cerebellar, reticular and basal ganglia control of movement
Motor dysfunction in various diseases of the central nervous system (pyramidal syndromes, ataxias, dystonia, parkinsonian syndromes.
Instructors:
D. Anastasopoulos

 

EYE MOVEMENTSTop of the page

Course Master:
D. Anastasopoulos
Duration:
1 semester
 
ECTS (credit hours):

6 (30)
Course outline:
Quantification of movement
Brainstem and spinal cord motor neurons
Premotor neurons
Sensory control of movement
Structure and function of anterior colliculus
Vestibular control of gaze
Cerebellar control of eye movements
Basal ganglia control of eye movements
Cortical control of eye movements
Simulations of oculomotor control
Diplopia and strabismus
Effects of vestibular failure on eye movements
Central disorders of ocular motility
Instructors:
D. Anastasopoulos

 

ANALYSIS AND MODELING OF SIGNALS AND SYSTEMS WITH APPLICATION TO NEUROMUSCULAR MECHANISMS IN MOTOR CONTROLTop of the page

Course Master:
C. Christakos
Duration:
1 semester
ECTS (credit hours):
9 (45)
Course outline:
1.    Signals and Systems (Introduction, stochastic processes, input-output relations for linear systems).
2.    Spectral Analysis (Introduction, estimation of power spectra and coherence, linear system identification).
3.    Correlation and Coherence Analysis (Introduction, techniques of analysis of population synchrony in the time- and frequency-domain).
4.    Analysis and Modeling of Neural Signals (Properties, mathematical mechanisms and computer models).
5.    Neuromuscular Mechanisms: Models of Muscle Force Generation (Population model of muscle, application to the study of muscle force and tremor genesis via mathematical modeling and computer simulations).
6.    Neuromuscular Mechanisms: Models of the Electromyogram (Use of the population model of muscle in the study of muscle electrical activity via mathematical modeling and computer simulations
7.    Muscle Receptors and Spinal Circuits (Role in the control of muscle contractions and movement, models of receptor activities as information carriers, model of enhanced muscle tremor).
Instructors:
C.N. Christakos and collaborators
Prerequisites:
Neurophysiology, Basic knowledge of calculus, probability theory and computer programming

 

MOLECULAR CELLULAR NEUROENDOCRINOLOGYTop of the page

Course Master:
R. Dermitzaki
Duration:
1 semester
ECTS (credit hours):
6 (30)
Course outline:

Neuroendocrinology of Stress

           Physiology of the stress axis

           CRH receptors and their antagonists
           Opioid receptors and their antagonists  
           ACTH receptors

           Animal models in the study of stress

           KO animals in the study of stress
           Glucocorticoid receptors

Neuroendocrinology of the Immune Response

           HPA axis-immune system interaction
           Neuroendocrine control of inflammation

Neuroendocrinology of Sleep

Neuroendocrinology of the Energy Balance
           General introduction:
           Appetite regulating neuropeptides

Neuroendocrinology of the Reproduction

           Neuroendocrine regulation of GnRH
           Neuroendocrine regulation of gonadal function

           Neuroendocrine regulation of the fetal-maternal unit

Neuroendocrinology of the Central Nervous System

           Neuropeptides:
           Neurosteroids
           Neurotrophic factors
           Membrane receptors of neuroactive steroids
Instructors:
R. Dermitzaki, M. Venyhaki

 

CORTICAL, SUBCORTICAL AND CEREBELLAR PROCESSES OF LEARNING AND MEMORYTop of the page

Course Master:
Yannis Dalezios
Duration:
One semester
ECTS (credit hours):
6 (30)
Course outline:
  1. Classical and operant conditioning.
  2. Cellular mechanisms of learning and memory.
  3. Neurobiology of learning and memory in humans.
  4. Pathology (syndromes, ageing)
  5. Anatomy of the cerebellum.
  6. Cerebellum and movement control. I.
  7. Cerebellum and movement control. II.
  8. Cerebellum and learning. a. Classical conditioning.
  9. Cerebellum and learning. b. Other types of learning.
  10. Cerebellum and cognition.
Instructors:
Yannis Dalezios and invited speakers.

 

SYNAPTIC INTERACTIONS IN THE CORTEXTop of the page

Course Master:
Yannis Dalezios
Duration:
One semester
ECTS (credit hours):
6 (30)
Course outline:
1.           Intoduction. Methods.
2.           Neuronal types.
3.           GABA receptors and their localization.
4.           Ionotropic glutamate receptors and their localization.
5.           Metabotropic Glutamate Receptors: from structure to function. I. (F. Ferraguti)
6.           Metabotropic Glutamate Receptors: from structure to function. II. (F. Ferraguti)
7.           Synaptic organisation of the cerebral cortex: Neuronal types, Connections, Receptors and their Physiological Roles. I (P. Somogyi)
8.           Synaptic organisation of the cerebral cortex: Neuronal types, Connections, Receptors and their Physiological Roles. II (P. Somogyi)
9.           The functional organisation of the basal ganglia I. (J.P. Bolam)
10.           The functional organisation of the basal ganglia II. (J.P. Bolam)
Instructors:
Yannis Dalezios, Peter Somogyi, J. Paul Bolam, Francesco Ferraguti.

 

DESIRES, VALUES, MOTIVES: A NEUROPHENOMENOLOGICAL POINT OF VIEWTop of the page

Course Master:
Panos Theodorou
Duration:
semester
ECTS (credit hours):
6 (30)
Course outline:
1. The problem: How does an intelligent comportment towards beings in a world come about?
2. Fundamental genealogy of the problem: recourse to Aristotle's De Anima (appetite, goods, movement).
3. The theory of motives/motivation in recent philosophical thought: Hume and Kant.
4. Modern Anglo-American treatment of motives/motivation.
5. Traditional Phenomenology and Neurophenomenology: from Husserl, Heidegger and Merleau-Ponty to Varela, Maturana and Thompson.
6. Un unexpected source of inspiration for the further development of Neurophenomenology: appetite, values and motives/motivation in Max Scheler's Formalism in Ethics and Non-Formal Ethics of Values (1913, 1916) and The Human's Place in the Cosmos (1928).
Instructors:
Panos Theodorou
Prerequisites:
 

 

NEUROTRANSMITTERS AND THEIR RECEPTORSTop of the page

Course Master:
G. Liapakis
Duration:
1 semester
ECTS (credit hours):
6 (30)         
Course outline:
  1. Neurotransmitters, neurotransmitter receptors and synaptic transmission.
  2. Neurotransmitter systems in the central nervous system (CNS). Abnormalities in the neurotransmitter systems of the CNS in pathophysiological conditions and pharmacological approaches for their treatment.
  3. Neurotransmitters and their receptors in the hypothalamic-pituitary-adrenal axis (HPA), and their role in stress.
  4. Elucidation of the role of neurotransmitters and their receptors in physiological and pathophysiological conditions, using knockout animals.
  5. G-proteins, intracellular signaling pathways, and neurotransmitter receptors coupled to G-proteins.
  6. Transcriptional regulation and G-protein coupled receptors.
  7. Regulation of function of G-protein coupled receptors.
  8. Studying the function of G-protein coupled receptors.
  9. Structure of G-protein coupled receptors and receptor activation-associated structural changes.
  10. Analysis of the structure and function of G-protein coupled receptors. Receptor-based drug design.
Instructors:
G. Liapakis, M. Venihaki
Prerequisites:
Cellular and Molecular Neuroendocrinology

 

 

OCULOMOTOR CONTROLTop of the page

Course Master:
A. Moschovakis
Duration:
One semester (Two hours per week)
ECTS (credit hours):
9 (45)
Course outline:
1.       Biomechanics of moving limbs
2.       Motoneurons
3.       Premotoneurons: The neural integrator
4.       Feedback control of movement parameters: The burst generator
5.       The Superior Colliculus: Metrics and sensorimotor interface.
6.       Vestibular control of eye movements
7.       Cerebellar control of eye movements
8.       Basal ganglionic control of eye movements
9.       Cortical control of eye movements
10.     Models of the oculomotor system
Instructors:
A. Moschovakis, D. Anastasopoulos
Prerequisites:
Systems and signals

 

COMPUTATIONAL VISIONTop of the page

Course Master:
A. Argyros
Duration:
1 semester
ECTS (credit hours):
4 (60)
Course Outline:
Detailed study of computational vision methods and systems that seek to produce a realistic interpretation of the world through the analysis of one or more images. The course includes a brief introduction to the field of image processing. Special attention is given to topics such as the study of intrinsic and extrinsic camera parameters, camera calibration, extraction of image features, understanding of the 3D structure of a scene from stereoscopic systems, motion perception, methods for object recognition and methods for image retrieval based on pictorial content. The course also includes presentation of specific applications in the context of integrated computational vision systems.
Instructors:
A. Argyros

 

CEREBRAL CORTEX AND COGNITIONTop of the page

Course Master:
Georgia Gregoriou, Vassilis Raos, Helen Savaki
Duration:
1 semester
ECTS (credit hours):
(45)
Course outline:
1. Primary and Secondary Visual Cortices. Neuronal properties and topographic organization.
2. Middle temporal area (MT). Experimental approaches to assess causal relationships between neuronal function and behavior.
3. Visual area V4.
4. Inferior Temporal cortex (IT). How complex visual stimuli are encoded in the brain.
5. From basic properties of visual neurons to visual awareness.
6. Frontal Eye Fields (FEF) and Lateral Intraparietal area (LIP).
7. Neural mechanisms of visual attention.
8. Cerebral circuits underlying visuomotor behavior in non human primates: ventral premotor area F5 - anterior intraparietal area (AIP).
9. Cerebral circuits underlying visuomotor behavior in non human primates: ventral premotor area F5 - primary motor cortex (MI).
10. Mirror neurons.
11. Cerebral circuits underlying visuomotor behavior in non human primates: ventral premotor area F4 - ventral intraparietal area (VIP).
12. Cerebral circuits underlying visuomotor behavior in non human primates: dorsal premotor area F2 - Area V6A.
13. Cerebral circuits underlying visuomotor behavior in non human primates
14. (i) Anatomy and physiology of prefrontal cortex. (ii) Consciousness
15. Embodied cognition: how we understand others' actions.
Instructors:
Georgia Gregoriou, Vassilis Raos, Helen Savaki
Prerequisites:
Neuroanatomy.

 

THE USE OF FUNCTIONAL IMAGING TECHNIQUES IN THE STUDY OF COGNITIVE FUNCTIONS IN MANTop of the page

Course Master:
N. Smyrnis
Duration:
1 semester
ECTS (credit hours):
(30)
Course outline:
Basic principles for the design of experiments using functional imaging techniques (the subtraction method of Donders).
Evoked potentials. Functional Imaging using High Density evoked potentials. |Signal processing and analysis.
Functional magnetic Resonance Imaging. basic principles of signal acquisition, processing and analysis.
Functional imaging in the study of visual perception: primary visual cortex.
Functional imaging in the study of visual perception: face and object recognition, temporal cortex.
Functional imaging in the study of motor control: I Primary motor cortex.
Functional imaging in the study of motor control: II.. Visuomotor integration, parietal cortex.
Functional imaging in the study of attention.
Functional imaging in the study of working memory.
Functional imaging in the study of higher cognitive functions (calculus, music etc)
Functional imaging in the study of language.
Functional imaging in the study of the porblem of consiousness.
Instructors:
N. Smyrnis
Prerequisites:
Basic knowledge of functional neuroanatomy

 

HUMAN COMPUTER INTERACTIONTop of the page

Course Master:
Constantine Stephanidis
Duration:
1 semester
ECTS (credit hours):
12 (60)
Course outline:
The aim of the course "Human-Computer Interaction" is to provide the theoretical base and the practical knowledge required for the design, development and evaluation of user interfaces.
  • Overview of the discipline concerned with Human-Computer Interaction.
  • The human, the computer and their interaction.
  • Input and Output devices. Cognitive frameworks, perception, representation and memory.
  • The development lifecycle of the user interfaces of interactive systems and software. Distinction between the user interface and the application code. Principles, rules and templates of user-centered design. User requirements analysis. Ergonomics, human factors and user interface usability.
  • Guidelines, standards and standard guides.
  • The basics of user interface development. Help and support to the user. Documentation. Introduction to user interface evaluation. User interfaces accessible by various user categories including people with different types of disabilities. User interface development for web applications and services.
  • Human-Computer Interaction in the Information Society: modern trends and approaches.
Instructors:
Constantine Stephanidis
Prerequisites:
 

 

CELLULAR MECHANISMS OF LEARNING AND MEMORYTop of the page

Course Master:
Kiki Sidiropoulou
Duration:
1 semester
ECTS (credit hours):
(30)
Course outline:
1. Behavioral tests for learning and memory in rodents.
2. Cellular correlates of memory: long-term potentiation and persistent activity 
3. Synaptic mechanisms of long-term potentiation: NMDA, AMPA and metabotropic glutamate receptors.
4. Other biophysical mechanisms involved in long-term potentiation and memory.
5. Biophysical mechanisms of persistent activity: NMDA receptor and CAN channels.
6. Cell-type specific control of neuronal activity in vivo: Effects on learning and memory processes.
7. Effect of learning experience on biophysical mechanisms.
Instructors:
Kyriaki Sidiropoulou

 
 

AUTONOMOUS ROBOTIC NAVIGATIONTop of the page

Course Master:
Panos Trahanias
Duration:
1 semester
ECTS (credit hours):
12 (60)
Course Outline:
The course aims at the presentation and study of the mechanisms that facilitate a robotic system to perceive its environment and use the relevant information to autonomously navigate in it. This involves topics such as sensory types and their principles of operation, mapping, localization, path planning and tracking, obstacle detection and avoidance, landmarks and topological navigation. The course includes a project based on a recent scientific paper.
Instructors:
Panos Trahanias

 

MEDICAL IMAGINGTop of the page

Course Master:
C. Marias
Duration:
1 semester
ECTS (credit hours):
12 (60)
Course Outline:
Medical imaging systems and physical principles of medical imaging modalities. Medical image reconstruction methods, as well as 2D and 3D medical image processing. Medical image analysis. Algorithms for the description and retrieval of medical images by content. Picture archiving and communicationsystems (PACS).
Instructors:
C. Marias

 

BIOMIMETIC ROBOTICSTop of the page

Course Master:
D. Tsakiris
Duration:
1 semester
ECTS (credit hours):
12 (60)
Course Outline:
This course will consider the mechanical behavior and the motion control of complex robotic systems inspired from biology. Some examples of such systems are robotic systems emulating the reptile undulatory locomotion, active perception systems inspired by the human oculomotor system and robotic systems inspired by the visual motion-based insect flight control system.
The course will draw on studies from computational neuroethology and the computational neurosciences, in order to address biomimetic robot control and the modeling of biological motion control systems. More precisely, it will address topics related to:
       the kinematics and dynamics of robotic systems,
       the control of robotic systems, with emphasis on linear and non-linear control, on sensor-based control, on the use of learning in control and on behavior-based control,
       the neural mechanisms for control of motion, such as the central pattern generator neural networks responsible for rhythmogenesis in biological systems.
Instructors:
D. Tsakiris

 

INTRODUCTION TO THE PHILOSOPHY OF PERCEPTIONTop of the page

Course Master:
Maria Venieri
Duration:
semester
ECTS (credit hours):
6 (30)
Course outline:
1. Main issues in the philosophy of perception.
2. History of the field from Aristotle to the 20th century.
3. Perception and the problem of the external world. The arguments from illusion and hallucination.
4. Arguments for and against indirect realist theories of perception
5. Arguments for and against direct realism
6. Adverbial theory of perception
        Active perception
7. The problem of perceptual content
8. The philosophical impact of psychological theories of perception (Bruner, Gibson, Marr)
9. Final assessment of the examined theories. Conclusions
Instructors:
M. Venieri

 

INTRODUCTION TO SOCIAL ANTHROPOLOGYTop of the page

Course Master:
George Nikolakakis
Duration:
semester
ECTS (credit hours):
6 (30)
Course Outline:
History of Social Anthropology
Branches and research objects
Anthropology and Social Sciences
Primitive and modern societiesBasic concepts in science and methodology
Qualitative and quantitative methods in Anthropology
Research and investigation on the spot
Interpretative approaches of institutions and fields
Selected analytical examples
Approaches of the symbolic systems
Instructors:
George Nikolakakis
Prerequisites:
None

 

ANTHROPOLOGY OF THE SYMBOLIC SYSTEMSTop of the page

Course Master:
George Nikolakakis
Duration:
1 semester
ECTS (credit hours):
9 (45)
Course Outline:
The concept of the symbolic system
Object, picture, symbol, sign
The symbolic exchange
Concept and approaches of the gift in "traditional" and modern societies
Language, thought and symbolic systems in primitive systems of categorization
Analytical examples of symbolic systemsApproaches of the political
Approaches of the religious
Approaches of the economic
Connections and correlations of the symbolic systems
Instructors:
George Nikolakakis
Prerequisites:
Introduction in Social Anthropology

 

HISTORY AND PHILOSOPHY OF PSYCHOLOGY AND PSYCHIATRYTop of the page

Course Masters:
K. Moutoussis, D. Nikolinakos
Duration:
1 semester
ECTS (credit hours):
9 (45)
Course Outline:

1. Introduction to the methodological problems to the social and human sciences.

2. About the concept of health and illness.

3. Experiments with human subjects

4. Rules and deviations.

5. Developmental and evolutionary problems of psychology.

6. Theories and practices about behavioral and mental illness.

7. Concept of therapy and healing.

Instructors:
K. Moutoussis
Prerequisites:
None

 

PRINCIPLES OF FUNCTIONAL IMAGING OF BRAIN MECHANISMS APPLIED TO fMRI DATATop of the page

Course Master:

Eleni Orfanidou, P. Simos

Duration:

1 semester

ECTS (credit hours):

8 (40)

Course Outline:

1. Principles of functional brain imaging

2. Principles of radiation physics applied to functional magnetic resonance imaging

3. Techniques used in the analysis of fMRI data

4. Use of fMRI in the study of linguistic brain mechanisms - Principles - Experimental design

5. Memory processes - Brain mechanisms - Experimental design

6. Use of fMRI in the study of linguistic brain mechanisms - A critical appraisal

7. Laboratory of fMRI data analysis - data conditioning (single-subject)

8. Laboratory of fMRI data analysis - statistics (single-subject)

9. Laboratory of fMRI data analysis - hypothesis testing (group-level)

10. Laboratory of fMRI data analysis - functional connectivity (CONN)

11. Use of functional brain imaging in the study of memory

12. Use of functional brain imaging in the study of emotions

Instructors:

E. Orfanidou, P. Simos, Th. Maris, E. Kavroulakis

Prerequisites:

 

 

EVOLUTIONARY COGNITIVE SYSTEMSTop of the page

Course Master:
M. Maniadakis
Duration
1 semester
ECTS (credit hours):
6 (30)
Course outline:
The course aims to provide basic knowledge in using evolutionary algorithms for the design and implementation of artificial cognitive systems. The course will particularly focus on (i) the exploitation of neuroscience observations for implementing brain-like cognitive dynamics, and (ii) the study of the internal mechanisms self-organized in the model as a means for extracting valuable hypothesis about brain functioning. The following topics will be covered:
• Interpreting cognitive systems design as an optimization problem.
• How evolutionary algorithms compare to other optimization methods.
• The encoding of the cognitive system.
• Solution evaluation and reproduction.
• Domain specific reproduction operators.
• Multi-criteria optimization approaches.
• Evolutionary developmental systems.
• Parallel evolutionary systems.
• Competitive co-evolution.
• Cooperative co-evolution.
Instructors:
M. Maniadakis
Prerequisites:
Basic programming skills

 

ALGORITHMS IN BIOINFORMATICSTop of the page

Course Masters
I. Tollis, I. Tsamardinos
Duration
1 semester
ECTS (credit hours):
10 (50)
Course outline:
 
Objectives of the course (preferably expressed in terms of learning outcomes and competences):
• Provide an introduction to the type of algorithmic problems and techniques that are widely used in the field of bioinformatics
• Familirize the students with the analysis of biological data and measurements in order to discovery new biological knowledge
 
Course contents:
The course starts with an introduction to the basic molecular biology concepts and types of biological data, such as gene expression micro-arrays, Single Nucleotide Polymorphism assays, etc. The introduction is oriented towards computer science students with no prior background in molecular biology.
A selection of algorithms used in bioinformatics from the list below is then presented:
• Basic statistical methods (hypothesis testing, multiple hypothesis testing and False Discovery Rate control) and methods for biomarker discovery. Applications to the discovery of differentially expressed genes.
• Basic methods of optimization in biomedical networks and graphs (metabolic networks, gene interaction networks, RNA/DNA interaction networks, gene interaction networks)
• Local and global string matching using dynamic programming and applications to the optimization of DNA structure.
• Modern methods for classification using Support Vector Machines and applications to the diagnosis and prediction of pathology from micro-array gene expression data.
• Modern and basic clustering algorithms and applications to the analysis of biological data for the identification of disease subtypes.
• Biomarker and molecular signature discovery using modern feature selection methods (Markov Blanket-based variable selection).
• Analysis of sequences based on Hidden Markov Models and application to biological sequences.
 
Recommended reading:
Reading material is selected among and provided by different books and papers in the scientific literature. The book "An Introduction to Bioinformatics Algorithms" by Neil C. Jones and Pavel A. Pevzner is followed loosely.
 
 
Teaching methods:
There are two weekly lectures that teach the main material of the course. These are supported by recitations taught at most once a week that delve into selected details of each week's material and go through the solutions to a selected list of exercises. In the course, there are weekly or biweekly exercises that contain a theoretical and a practical (programming) part. Programming is performed mostly in the Matlab environment.
 
Assessment methods:
The final grade is a linear function of the grades of the final exam and the assignments with weights 70, 30. Language of instruction: The language is Greek or English depending on the audience. English speaking students are welcome.
Instructors:
 I. Tollis, I. Tsamardinos
Prerequisites:
CS-380, CS-217, MΑΘ-105

 

MACHINE LEARNINGTop of the page

Course Master
I. Tsamardinos
Duration
1 semester
ECTS (credit hours)
10 (50)
Course outline:
 
Objectives of the course (preferably expressed in terms of learning outcomes and competences):
• To provide an introduction to the type of problems addressed in the field of Machine Learning, the relation with other related fields, and familiarize the students with the major ideas, theoretical results, techniques, algorithms, and methods of the field
• To teach the programming of simple Machine Learning algorithms
• To enable the student to perform simple, yet effective and methodologically sound data analysis, provide prognostic models, perform variable selection, tune the algorithm parameters, and provide reliable prediction performance estimates
• To enable the student to assess the basic theoretical and practical advantages and disadvantages of a learning algorithm
• To familiarize the student with general methods for casting problems as Machine Learning problems and general methods for representing the data appropriately
 
Course contents:
a) Basic statistical methods employed in Machine Learning, such as simple hypothesis testing b) Basic learning algorithms for supervised learning, such as Bayesian Classifiers, Decision Trees, Feed-Forward Neural Networks, k-Nearest Neighbors, and Support Vector Machines. c) Metrics of performance, such as accuracy and the Area Under the Receiving Operating Characteristic curve d) Methods of estimating performance and optimization of parameter values, such as cross-validation and nested cross-validation e) Issues of data cleaning and representation f) More advanced methods : variable selection techniques (e.g., Univariate Association Filtering, Recursive Feature Elimination, Wrapping search, Bayesian Network-based variable selection), and Causal Discovery methods g) Selected examples of application of Machine Learning methods h) Overview of other learning problems and paradigms (unsupervised methods, clustering, relational learning, learning with timed data, active learning, etc.)
 
Recommended reading: Reading material is selected among and provided by different books and papers in the scientific literature. The books mostly influencing the class are: a) Machine Learning, by Tom Mitchell and b) The Elements of Statistical Learning: Data Mining, Inference, and Prediction , by Trevor Hastie, Robert Tibshirani, Jerome Friedman
 
Teaching methods: There are two weekly lectures that teach the main material of the course. These are supported by recitations taught weekly that delve into selected details of each week's material and go through the solutions to a selected list of exercises. In the course, there are weekly or biweekly exercises that contain a theoretical and a practical (programming) part. Programming is performed in the Matlab programming environment. During the third part of the course, the students are requested to complete a project; the topic is selected and agreed with the instructor.
 
Assessment methods:
The final grade is a linear function of the grades of the final exam, the midterm exam, the assignments, and the project with weights 30, 20, 20, 30.

Language of instruction:
The language is Greek or English depending on the audience. English speaking students are welcome.
Instructors:
I. Tsamardinos
Prerequisites:
CS-150, CS-217, CS-380

 

INTRODUCTION TO ARTIFICIAL INTELLIGENCETop of the page

Course Master
I. Tsamardinos
Duration
1 semester
ECTS (credit hours):
10 (50)
Course outline:
 
Objectives of the course (preferably expressed in terms of learning outcomes and competences):
• to provide an introduction to the theory, practice and philosophy of Artificial Intelligence (AI) as a field
• to study in depth several basic and fundamental algorithmic techniques of AI, particularly techniques that are widely used in other fields too
• to familiarize the students with some of the basic programming tools of the field and other programming paradigms, such as functional programming in Lisp and symbolic programming
 
Course outline:
• Introduction to the problems and history of Artificial Intelligence
• Problem solving techniques using searching, including informed and uniformed search, as well as constraint satisfaction techniques
• Logic-based agents
• Representing problems and reasoning in Propositional and First Order Logics
• Planning
• An introduction to reasoning with uncertainty, making simple decisions under uncertainty
 
Recommended reading:
Artificial Intelligence: A Modern Approach, by S. Russell and P. Norvig
 
Teaching methods:
There are two weekly lectures that teach the main material of the course. These are supported by recitations taught at most once a week that delve into selected details of each week's material and go through the solutions to a selected list of exercises. In the course, there are weekly or biweekly exercises that contain a theoretical and a practical (programming) part. Programming is performed in the Allegro Lisp programming environment.
 
Assessment methods:
The final grade is a linear function of the grades of the final exam, the midterm exam, and the assignments with weights 40, 25, 35.
 
Language of instruction:
The language is Greek or English depending on the audience. English speaking students are welcome.
Instructors:
I. Tsamardinos
Prerequisites:
CS-240, CS-180

 

FOUNDATIONS OF COGNITIVE SCIENCE AND UNIFIED THEORIES OF COGNITIVE SYSTEMS Top of the page

Course Master:
Petros A. M. Gelepithis
Duration
1 semester
ECTS (credit hours):
12 (60)
Course outline:
To offer a concise, interdisciplinary review of the foundations on which the study of cognitive systems is based. On successfully finishing the course, the students will have delved into the main research issues in the foundations of the sciences of brain and mind. Foundations of Cognitive Science and Unified Theories of Cognitive Systems: Basic notions and tools. Computational systems of knowledge representation: Philosophical, neurophysiological, and computational issues. The Human Language as tool and knowledge system. Human and Robotic emotions: Theories, problems, and mechanisms. Interactions between logic and emotion. Comparative review of theories of consciousness: philosophical, neurophysiological, computational, psychological. Comparative presentation of unified theories of cognition: Psychological, computational, neurophysiological. A novel, axiomatic theory of cognitive systems: Consequences for the sciences of brain and mind. Students' assessment will be entirely based on a written research essay. Literature: Anderson, J. R., & Lebiere, C. (2003). The Newell Test for a theory of cognition. Behavioral and Brain Sciences. 26: 587-640 (including commentary and response by the authors). Bennett, M., Dennett, D., Hacker, P., & Searle, J. R. (2007). Neuroscience and Philosophy: Brain, Mind, and Language. Columbia University Press. Boden, M. A. ed. (1990). The philosophy of artificial intelligence. Oxford University Press. Branquinho, J. ed. (2001). The Foundations of Cognitive Science. Clarendon Press, Oxford. Dautenhahn, K. (2007). Socially intelligent robots: dimensions of human–robot interaction. Phil. Trans. R. Soc. B, 362: 679–704. Merker, B. (2007). Consciousness without a cerebral cortex: A challenge for neuroscience and medicine. Behavioral and Brain Sciences, 30: 63-134 Newell, A. (1990). Unified theories of cognition. Harvard University Press. Newen, A., & Bartels, A. (2007). Animal Minds and the Possession of Concepts Philosophical Psychology, 20, 3, 283-308. Seth, A. K., Baars B. J., & Edelman, D. B. (2005). Criteria for consciousness in humans and other mammals. Consciousness and Cognition, 14: 119-139 Sirois, S., Spratling, M., Thomas, M. S. C., Westermann G., Mareschal, D., & Johnson M., H. (2007). Précis of: Neuroconstructivism: How the Brain Constructs Cognition. Behavioral and Brain Sciences, (in press).
Instructors:
Petros A. M. Gelepithis

 

BRAIN CONNECTIVITY ANALYSIS USING EEG/ MEG Top of the page

Course Master:
V. Sakkalis
Duration
1 semester
ECTS (credit hours):
6 (30)
Course outline:
Functional Imaging Modalities, EEG/ MEG signals and facts, Cross-correlation & Coherence, Short time Fourier Transform Coherence, Wavelet Coherence, Phase Synchronization, Deterministic Chaos, Nonlinear interdependence measures, Surrogate time series analysis, Topographic Brain Mapping, Brain Network Visualization and Quantitative analysis using Graphs, Source localization techniques
Instructors:
V. Sakkalis

 

ΝEUROENDOCRINOLOGY Top of the page

Course Master:
A.Margioris
Duration
1 semester
ECTS (credit hours):
6 (30)
Course outline:

Νeuroendocrinology of Stress

Physiology of the Stress axis

CRH receptors and their antagonists

ACTH receptors

Opioid receptors and their antagonists

Glucocorticoid receptors

Animal models of stress

Neuroendocrinology of the immune system

Immune-neuroendocrine interactions

Neuroendocrine regulation of inflammation

Neuroendocrinology of sleep

Neuroendocrinology of energy homeostasis

Introduction

Appetite of Neuropeptides

Reproductive Neuroendocrinology

Neuroendocrine regulation of GnRH

Neuroendocrine regulation of Gonads

Neuroendocrine regulation of the Fetoplacental unit

Neuroendocrinology of the Central Nervous system

Neuropeptides

Neurosteroids

Neurotrophic factors (Neurotrophins)

Membrane receptors of Neurosteroids

Instructors:
A.Margioris, Ch.Tsatsanis, A.Makrygiannakis, A.Chatzoglou, G.Chrousos, M.Venyhaki, G.Liapakis, S.Tsagarakis, E.Castanas, I.Charalambopoulos

 

INTRODUCTION IN MOLECULAR NEUROBIOLOGYTop of the page

Course Master:
I. Charalampopoulos
Duration:
1 semester
ECTS (credit hours):
6 (30)
Course outline:
Introduction to Molecular Neurobiology: from structure to therapeutics.
Neuronal interactions at the molecular level.
Mechanisms of neuroprotection and neurorepair.
Neuroregeneration in the CNS and PNS: molecular mechanisms.
Adhesion molecules and ECM in neural tissue.
Glial cells and regeneration/remyelination. (Use of the population model of muscle in the study of muscle electrical activity via mathematical modeling and computer simulations
Neural stem cells biology-Adult neurogenesis.
Neurosteroids, neurotransmitters and neuropeptides in Nervous System.
Interactions of Nervous and Immune systems.
Animal models of neurodegeneration.
Neurodegenerative diseases: pathophysiology and therapeutics.
Instructors:
I. Charalampopoulos
Prerequisites:
Basic Neurosciences